Lucy Knight from ER
Lucy Knight’s (Kellie Martin) death was a defining moment for the staff of County General Hospital, who banded together to try and save her and Carter (Noah Wyle) after the two were stabbed by patient Paul Sobriki (David Krumholtz). The promising med student’s murder was so painful to bear that even Romano (Paul McCrane) broke down; it also served as the catalyst for Carter’s narcotics addiction, who suffered from survivor’s guilt in the wake of her death.
Jen Lindley from Dawson’s Creek
In the series finale, Jen Lindley (Michelle Williams) got the short end of the stick after serving as the backbone of Dawson’s Creek for so long. By the end of the show, she’d become the single mother of a one-year-old girl. Sadly, after fainting, Jen revealed that she suffered from an incurable heart condition that would kill her at the age of only 25.
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