Charlie Pace from Lost
Three words: “Not Penny’s Boat.” In Charlie’s (Dominic Monaghan) heroic final hour, he managed to convey the message to Desmond Hume (Henry Ian Cusik), for whom he willingly sacrificed his own life—his long lost love Penny hadn’t sent rescuers to save him. Charlie’s death demonstrated that he had undergone an honest transformation; by the time he took his last breaths, Charlie was the best possible version of himself.
Denny Duquette from Grey’s Anatomy
Cue ugly sobbing. Grey’s Anatomy has seen an ongoing stream of endless tragedies come through the doors of Grey-Sloan Memorial, but one of the hardest-hitting losses was that of Denny Duquette (Jeffrey Dean Morgan). His death came at a time when the casualty count on Grey’s hadn’t yet reached peak levels of tragedy, which made it cut even deeper. Izzie (Katherine Heigl), then an intern, developed a bond with the smooth-talking patient, and she ended up jeopardizing her career to move him up on the heart transplant list. Unfortunately, Denny still passed away after the transplant due to a blood clot, destroying the hearts of millions… poor Izzie included.
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